Nucleophilic Phosphine Catalysis: The Untold Story. Issue 11 (29th September 2021)

• Record Type: Journal Article
• Authors: Khong, San; Venkatesh, Telugu; Kwon, Ohyun
• Is Part Of: Asian journal of organic chemistry. Volume 10:Issue 11(2021)
• Page Start: 2699
• Page End: 2708
• Publication Date: 2021-09-29
• Subjects: phosphine catalysis -- Lewis base -- organocatalysis -- phosphonium zwitterion -- phosphonium ylide; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; 547.005
• DOI: 10.1002/ajoc.202100496
• Languages: English
• ISSNs: 2193-5807

Abstract

Abstract: This Minireview provides insight into the early history of nucleophilic phosphinocatalysis. The concepts of 1, 4‐addition of a tertiary phosphine to an α, β‐enone and of equilibrium between the resulting phosphonium zwitterion and phosphonium ylide established a fundamental basis for the development of several classical transformations, including the Rauhut‐Currier, Morita, McClure‐Baizer‐Anderson, and Oda reactions. Abstract : To set the record straight : This Minireview provides insight into the early history of nucleophilic phosphine catalysis. The concepts of 1, 4‐addition of a tertiary phosphine to an α, β‐enone and of equilibrium between the resulting phosphonium zwitterion and phosphonium ylide established a fundamental basis for the development of several classical transformations, including the Rauhut‐Currier, Morita, McClure‐Baizer‐Anderson, and Oda reactions.