Transient Pancytopenia Subsequently Diagnosed With Acute Leukemia: A Report of 4 Cases of Acute Lymphoblastic Leukemia and Acute Myeloid Leukemia. Issue 5 (26th July 2021)

• Record Type: Journal Article
• Authors: Kirk, Susan E.; Young, Elizabeth; Ray, Anish; Dzurik, Yvette; Elghetany, Tarek; Sasa, Ghadir
• Is Part Of: Journal of pediatric hematology/oncology. Volume 43:Issue 5(2021)
• Page Start: e715
• Page End: e717
• Publication Date: 2021-07-26
• Subjects: Preleukemia -- leukemia -- transient pancytopenia; Pediatric hematology -- Periodicals; Tumors in children -- Periodicals; 618.9215
• DOI: 10.1097/MPH.0000000000001922
• Languages: English
• ISSNs: 1077-4114

Abstract

Abstract : A transient pancytopenic phase has been described in pediatric leukemia. The characteristic complete recovery of peripheral counts can obscure a clinician's suspicion for malignancy and may impact subsequent follow-up care. The authors describe 4 pediatric patients that had transient pancytopenia with an initial abnormal marrow finding. These patients were subsequently diagnosed with acute leukemia within 5 months of presentation. Awareness of this phenomenon by the provider and education of families may help with the appropriate and timely diagnosis of subsequent leukemia.