A–DA′D–A fused-ring small molecule-based nanoparticles for combined photothermal and photodynamic therapy of cancer. Issue 90 (29th October 2021)

• Record Type: Journal Article
• Authors: Lu, Bing; Zhang, Zhecheng; Jin, Danni; Yuan, Xiaolei; Wang, Jin; Ding, Yue; Wang, Yang; Yao, Yong
• Is Part Of: Chemical communications. Volume 57:Issue 90(2021)
• Page Start: 12020
• Page End: 12023
• Publication Date: 2021-10-29
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/d1cc04629b
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : Novel nanoparticles based on the A–DA′D–A conjugated small molecule Y6 for highly effective combined photothermal and photodynamic therapy of cancer. Abstract : New nanoparticles (Y6 NPs) based on the A–DA′D–A fused-ring conjugated small molecule Y6 have been prepared for the combined photothermal and photodynamic therapy of cancer. Y6 NPs show excellent light absorption from 300 to 900 nm, a good photothermal conversion efficiency of 57% and reactive oxygen species generation capability. The high photothermal conversion ability and superior photodynamic activity of Y6 NPs endow them with great potential for cancer therapy.