Molecular rotors as reporters for viscosity of solutions of collagen like peptides. Issue 43 (27th October 2021)

• Record Type: Journal Article
• Authors: McTiernan, Christopher D.; Zuñiga-Bustos, Matias; Rosales-Rojas, Roberto; Barrias, Pablo; Griffith, May; Poblete, Horacio; Sherin, Peter S.; López-Duarte, Ismael; Kuimova, Marina K.; Alarcon, Emilio I.
• Is Part Of: Physical chemistry chemical physics. Volume 23:Issue 43(2021)
• Page Start: 24545
• Page End: 24549
• Publication Date: 2021-10-27
• Subjects: Chemistry, Physical and theoretical -- Periodicals; 541.3
• DOI: 10.1039/d1cp04398f
• Languages: English
• ISSNs: 1463-9076

Abstract

Abstract : A BODIPY molecular rotor can be used to evaluate the viscosity of collagen-like peptide-PEG solutions. Abstract : We have studied the suitability of using a molecular rotor-based steady-state fluorometric assay for evaluating changes in both the conformation and the viscosity of collagen-like peptide solutions. Our results indicate that a positive charge incorporated on the hydrophobic tail of the BODIPY molecular rotor favours the dye specificity as a reporter for viscosity of these solutions.