Age and clinical outcomes after hip fracture surgery: do octogenarian, nonagenarian and centenarian classifications matter?. (3rd July 2021)

• Record Type: Journal Article
• Authors: Ogawa, Takahisa; Schermann, Haggai; Kobayashi, Hiroki; Fushimi, Kiyohide; Okawa, Atsushi; Jinno, Tetsuya
• Is Part Of: Age and ageing. Volume 50:Number 6(2021)
• Page Start: 1952
• Page End: 1960
• Publication Date: 2021-07-03
• Subjects: older people -- centenarian -- nonagenarian -- octogenarian -- older patients -- hip fracture -- in-hospital complications; Aging -- Periodicals; Geriatrics -- Periodicals; 618.97
• DOI: 10.1093/ageing/afab137
• Languages: English
• ISSNs: 0002-0729

Abstract

Abstract: Background: older patients with hip fractures are arbitrarily classified as octogenarians, nonagenarians and centenarians. We have designed this study to quantify in-hospital mortality and complications among each of these groups. We hypothesised that the associations between age and in-hospital mortality and complications are continuously increasing, and that these risks increase rapidly when patients reach a certain age. Methods: this research is a retrospective cohort study using nationwide database between 2010 and 2018. Patients undergoing hip fracture surgery, and aged 60 or older, were included. The associations between patient age, in-hospital mortality and complications were visualised using the restricted cubic spline models, and were analysed employing multivariable regression models. Then, octogenarians, nonagenarians and centenarians were compared. Results: among a total of 565, 950 patients, 48.7% ( n = 275, 775) were octogenarians, 23.0% ( n = 129, 937) were nonagenarians and 0.7% ( n = 4, 093) were centenarians. The models presented three types of association between age, in-hospital mortality and complications: (i) a continuous increase (mortality and respiratory complications); (ii) a mild increase followed by a steep rise (intensive care unit admission, heart failure, renal failure and surgical site hematoma) and (iii) a steep increase followed by a limited change (coronary heart disease, stroke and pulmonary embolisms). Conclusion: we identified three types of association between age and clinical outcomes. Patients aged 85–90 may constitute the upper threshold for age categorisations, because the risk of in-hospital complications changed dramatically at that stage. This information can improve clinical awareness of various complications and support collective decision-making.