New cases of human dirofilariosis on the Balkan Peninsula – "Masked intruders" uncovered by a surgeon. (February 2022)

• Record Type: Journal Article
• Authors: Momčilović, Stefan; Gabrielli, Simona; Đenić, Nebojša; Živković, Nataša; Stevanović, Goran; Krstić, Miljan; Ranđelović, Marina; Tasić-Otašević, Suzana
• Is Part Of: Parasitology international. Volume 86(2022)
• Publication Date: 2022-02
• Subjects: Differential diagnosis -- Human dirofilariosis -- Prevalence -- Subcutaneous nodules -- Treatment; Parasitology -- Periodicals; Parasites -- Periodicals; Parasitic Diseases -- Periodicals; Parasitology -- Periodicals; Parasitologie -- Périodiques; 571.99905
• DOI: 10.1016/j.parint.2021.102482
• Languages: English
• ISSNs: 1383-5769

Abstract

Abstract: Dirofilaria spp. nematodes are accidental parasites of humans causing mild to serious, superficial or visceral infections. Superficial dirofilariosis is rather common in Europe and is typically manifested as subcutaneous form. Herein we report 46 new cases of human dirofilariosis (19 patients with subcutaneous, 18 patients with ocular, 4 patients wih genital, 2 patients with submucosal, 2 patients with pulmonary and 1 patient with intramuscular form of infection) that were recorded from the beginning of 2015 to May 2021 on the Balkan Peninsula with a goal to update the prevalence of this parasitosis and point out potential problems in diagnosis and treatment. Besides, given the high possibility of misinterpretation as tumor, our second aim was to encourage the inclusion of this pathogen in the differential diagnosis of subcutaneous nodules. Although quite common forms, subcutaneous and ocular dirofilariosis can be very often misdiagnosed in clinical practice due to the absence of specific clinical manifestations. Therefore, raising awareness of clinicians about this zoonosis is needed as well as closer collaboration between physicians and veterinarians. Highlights: Forty-six new cases of human dirofilariosis were reported since 2015 in the Balkans. The largest number of cases was recorded in Bulgaria and Croatia. Pulmonary dirofilariosis was reported in 2 patients from Greece. Female sex was more often affected by the infection. Dirofilariosis is still a diagnostic challenge even for the experienced physicians.