Synthesis of arylboronates via the Pd-catalyzed desulfitative coupling reaction of sodium arylsulfinates with bis(pinacolato)diboron. (23rd November 2021)

• Record Type: Journal Article
• Authors: Qiu, Di; Li, Songyi; Yue, Guanglu; Mao, Jinshan; Xu, Bei; Yuan, Xinyu; Ye, Fei
• Is Part Of: Tetrahedron letters. Volume 85(2021)
• Publication Date: 2021-11-23
• Subjects: Palladium catalysis -- Desulfitative -- Cross-coupling -- Sodium arylsulfinates -- Arylboronate; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2021.153478
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: Abstract: The desulfitative borylation reaction of sodium arylsulfinates with bis(pinacolato)diboron or bis(neopentylglycolato)diboron under palladium catalysis has been developed, allowing selective C-B bond formation to give arylboronates with a range of functional groups in moderate to good yields under mild reaction conditions. A gram-scale preparation as well as the cascade Suzuki-Miyaura cross-coupling of arylboronates demonstrated the potential practical utility in organic synthesis.