Fits, feet and HIV: lessons from a case of coexisting epilepsy and neuropathy in a patient with perinatally acquired HIV-1 infection. (16th October 2018)

• Record Type: Journal Article
• Authors: Freeman-Romilly, Nell; Mewasingh, Leena; Coomer, Annette; Foster, Caroline
• Is Part Of: BMJ case reports. Volume 2018
• Publication Date: 2018-10-16
• Subjects: Hiv / Aids -- neuromuscular disease -- peripheral nerve disease -- child and adolescent psychiatry (paediatrics) -- neurology; Medicine -- Case studies -- Periodicals; 610.5
• DOI: 10.1136/bcr-2018-226042
• Languages: English
• ISSNs: 1757-790X

Abstract

Abstract : An 18-year-old black African man with well-controlled perinatally acquired HIV-1 was diagnosed in late adolescence with the unrelated diagnoses of Charcot-Marie-Tooth type 1A (CMT1A), epilepsy due to polymicrogyria and subsequently developed severe depression. The CMT1A diagnosis occurred after transfer of care from a local paediatric HIV service to a tertiary paediatric referral centre and was precipitated by recognition of a history and neurological signs not typically associated with perinatal HIV. The case resulted in the establishment of a quarterly combined paediatric HIV and paediatric neurology multidisciplinary team clinic to assess children and adolescents living with HIV with neurological symptoms.