Schizophrenia and Dental Health: A Systematic Review. Issue 9 (September 2021)

• Record Type: Journal Article
• Authors: Comparelli, Anna; Stampatore, Lorenzo; Costacurta, Micaela; Pompili, Maurizio
• Is Part Of: Journal of nervous and mental disease. Volume 209:Issue 9(2021)
• Page Start: 684
• Page End: 690
• Publication Date: 2021-09
• Subjects: Schizophrenia -- psychiatry -- antipsychotic drugs -- negative symptoms -- neuroinflammation -- dental health -- oral health -- DMFT -- caries -- periodontal; Neurology -- Periodicals; Psychiatry -- Periodicals; Neurology; Psychiatry; Neurologie; Psychiatrie; Neurology; Psychiatry; Periodicals; 616.8005
• DOI: 10.1097/NMD.0000000000001371
• Languages: English
• ISSNs: 0022-3018

Abstract

Abstract: Schizophrenia is characterized not only by psychopathological symptoms but also by medical comorbidities. Among the latter, there are limited data on dental health. We conducted a systematic review with the primary aim of clarifying the extent of the relationship between dental diseases and schizophrenia. The second aim was to delineate an intervention program based on illness-related factors that influence dental health. The preferred reporting items for systematic reviews and meta-analyses statement for reporting systematic reviews was used. Only articles published in English language peer-reviewed journals were considered; we excluded case reports, meta-analyses, and systematic reviews, as well as studies that did not clearly report statistical analysis, diagnostic criteria, or the number of patients included. Twenty-one studies comprising 13, 110 patients with schizophrenia and 9025 healthy controls were included. Negative symptomatology, long duration of illness, smoking habit, drug-induced xerostomia, and neuroinflammation are the most critical areas. We suggest an intervention program for prevention and treatment of dental diseases in schizophrenia.