EP706 Impact of malignant gynecological disease on occurrence of surgical site infection. (1st November 2019)

• Record Type: Journal Article
• Authors: Stefanovic, A; Likic Ladjevic, I; Kadija, S; Dotlic, J; Vilendecic, Z; Pilic, I; Pantovic, S; Stefanovic, K; Beleslin, A; Topuzovic, N
• Is Part Of: International journal of gynecological cancer. Volume 29(2019)Supplement 4
• Page Start: A401
• Page End: A401
• Publication Date: 2019-11-01
• Subjects: Generative organs, Female -- Cancer -- Periodicals; 616.99465
• DOI: 10.1136/ijgc-2019-ESGO.760
• Languages: English
• ISSNs: 1048-891X

Abstract

Abstract : Introduction/Background: Surgical site infections (SSI) in gynaecology are still common. However, it is debated whether malignancy is an independent risk factor for SSI. Therefore, the study aim was to investigate the impact of malignant gynaecological disease on surgical site infection occurrence after abdominal surgical procedure. Methodology: Study included all patients with SSI in three years period (2016–2018). Preoperatively general data as well as detailed medical history were taken from all patients. Surgical procedures were classified as classic or radical. In case of possible SSI signs (red, hot, discharge) swabs were taken from the wound. SSI was diagnosed based on the swab findings and infectious agents causing SSI were registered. Patients were divided according to surgery indications to study group (gynaecological malignancy) and control group (benignant disease excluding inflammatory conditions). Pre and postoperative data were compared and statistically analysed. Results: Study included 138 patients who in average had 55.71±14.18 years of age and 27.45±6.22 Body Mass Index. There were no significant differences between patients with SSI regarding their diagnosis (67 gynaecological malignancies; 71 benignant conditions; χ 2 =0.116; p=0.733; carcinoma of the cervix 14; uterus 25; ovary 28; χ 2 =4.866; p=0.088). However, in patients with gynaecological malignancies SSI was more often registered in more advanced disease stage (χ 2 =17.403; p=0.001) and if radical surgery was performed (χ 2 =12.014; p=0.001). In both patients with malignant and benign conditions the most common infectious agents were Staphylococcus (52.9%) and Enterococcus (26.8%) species, while other microbes were rather rare (χ 2 =69.594; p=0.001). Conclusion: Malignancy was not proven as independent risk factor for SSI after abdominal gynaecological surgical procedure. However, SSI is more likely to happen in more advanced stages of gynecological malignancy that require radical surgery. Disclosure: Nothing to disclose.