EP897 Clinical application of the sentinel lymph node technique in early ovarian cancer: phase II clinical trial. (1st November 2019)

• Record Type: Journal Article
• Authors: Lago, V; Bello, P; Montero, B; Matute, L; Padilla-Iserte, P; Lopez, S; Agudelo, M; Domingo, S
• Is Part Of: International journal of gynecological cancer. Volume 29(2019)Supplement 4
• Page Start: A485
• Page End: A485
• Publication Date: 2019-11-01
• Subjects: Generative organs, Female -- Cancer -- Periodicals; 616.99465
• DOI: 10.1136/ijgc-2019-ESGO.944
• Languages: English
• ISSNs: 1048-891X

Abstract

Abstract : Introduction/Background: There is limited evidence favoring the use of the sentinel lymph node technique in ovarian cancer, and no standardized approach has been studied. The objective of the present pilot study and clinical trial is to determine the feasibility of the sentinel lymph node technique by applying a clinical algorithm and the use of 99mTc and indocyanine green for its detection. Methodology: Patients with confirmed ovarian cancer were included. 99mTc and indocyanine green were injected into the ovarian and infundubulo-pelvic ligament stump. A gamma probe and near-infrared fluorescence imaging were used for sentinel lymph node detection. Results: The sentinel lymph node technique was performed in 10 patients in the pilot study and in 20 patients in the clinical trial with a detection rate in the pelvic and/or para-aortic region of 100%. Conclusion: The sentinel lymph node technique appears to be applicable in early-stage ovarian cancer with excellent detection rate. further studies are needed to establish the negative predictive value of the technique. Disclosure: Nothing to disclose.