123 Minimally invasive surgery versus laparotomy in HGS EOC patients in a teaching referral center. (13th November 2020)

• Record Type: Journal Article
• Authors: Ribeiro, B; Linhares, J; Ribeiro, R; Tsunoda, A
• Is Part Of: International journal of gynecological cancer. Volume 30(2020)Supplement 3
• Page Start: A55
• Page End: A56
• Publication Date: 2020-11-13
• Subjects: Generative organs, Female -- Cancer -- Periodicals; 616.99465
• DOI: 10.1136/ijgc-2020-IGCS.105
• Languages: English
• ISSNs: 1048-891X

Abstract

Abstract : Introduction: Complete cytoreduction represents a significant impact in OS for EOC patients. A large longitudinal incision is the standard access to achieve this goal. The aim of this study is to evaluate the role of MIS in interval debulking at a teaching institution. Methods: 126 HGS EOC patients referred for primary treatment in a referral cancer center, from 2014 and 2018, were included. Almost all patients underwent a laparoscopic diagnostic and peritoneal carcinomatosis index evaluation (PCI) before therapy. PS>2, PCI>20 and ASA>3 were indicators for neoadjuvant therapy. Results: 16 MIS and 79 laparotomic debulking procedures were identified. Interval debulking was proposed in 9 (23.6%) MIS and 29 (76.4%). Most patients were stage III and IV. A complete cytoreduction was achieved in all MIS patients. MIS had shorter hospital stay (1.5 versus 4.3 days), with no Grade 3 or more complications. Post-operative chemotherapy started in 29.7 days in MIS and 53.6 days in laparotomy. At a mean 24 months follow-up, 44.4% and 54.6% were free of disease at MIS and laparotomy groups, respectively. Conclusion: MIS may be an interesting approach to complete interval cytoreduction in very selected cases, with reduced complications and time to chemotherapy, with comparable DFS.