Whole body elemental composition during drug treatment of rheumatoid arthritis: a preliminary study. Issue 2 (April 1979)

• Record Type: Journal Article
• Authors: Kennedy, A C; Boddy, K; Williams, E D; Elliott, A T; Harvey, I; Holloway, I; Haywood, J K
• Is Part Of: Annals of the rheumatic diseases. Volume 38:Issue 2(1979)
• Page Start: 137
• Page End: 140
• Publication Date: 1979-04
• Subjects: Rheumatism -- Periodicals; 616.723005
• DOI: 10.1136/ard.38.2.137
• Languages: English
• ISSNs: 0003-4967

Abstract

Abstract : Thirty-two female patients with rheumatoid arthritis were divided into 3 groups and treated for 6 months with prednisolone, depot tetracosactrin, or indomethacin. Their whole body content of calcium, phosphorus, and nitrogen was measured before and after 3 and 6 months' treatment by in-vivo neutron activation analysis. No significant changes in these body elements were observed as a result of the treatments. The average amounts of calcium, phosphorus, and nitrogen were lower than normal in these patients, a finding consistent with the frequent observation of osteoporosis and muscle wasting in rheumatoid arthritis.