Peripheral nerve granuloma in a patient with tuberculosis. Issue 6 (1st December 2002)

• Record Type: Journal Article
• Authors: Orrell, R W; King, R H M; Bowler, J V; Ginsberg, L
• Is Part Of: Journal of neurology, neurosurgery and psychiatry. Volume 73:Issue 6(2002)
• Page Start: 769
• Page End: 771
• Publication Date: 2002-12-01
• Subjects: tuberculosis -- neuropathy -- granuloma; Neurology -- Periodicals; Nervous system -- Surgery -- Periodicals; Psychiatry -- Periodicals; 616.8
• DOI: 10.1136/jnnp.73.6.769
• Languages: English
• ISSNs: 0022-3050

Abstract

Abstract : The cause of peripheral neuropathy associated with tuberculosis is controversial. Possibilities include an immune mediated neuropathy, direct invasion of nerves, vasculitic neuropathy, compressive neuropathy, a meningitic reaction, and the toxic effects of antituberculous chemotherapy. This report describes the unusual finding of granulomas in the peripheral nerve of a patient with tuberculosis. The pathological findings were of a delayed hypersensitivity reaction, but with no more specific indications of the mechanism of the neuropathy.