Experience with cellulose acetate-coated activated charcoal haemoperfusion in the treatment of severe hypnotic drug intoxication. Issue 661 (November 1980)

• Record Type: Journal Article
• Authors: Crome, P.; Hampel, G.; Widdop, B.; Goulding, R.
• Is Part Of: Postgraduate medical journal. Volume 56:Issue 661(1980)
• Page Start: 763
• Page End: 766
• Publication Date: 1980-11
• Subjects: Medicine -- Periodicals; 610
• DOI: 10.1136/pgmj.56.661.763
• Languages: English
• ISSNs: 0032-5473

Abstract

Abstract : A haemoperfusion column containing activated charcoal coated with cellulose acetate was used to treat 7 patients with barbiturate or ethchlorvynol poisoning. Six of the patients showed marked lightening of coma and all showed a significant fall in plasma drug concentration. Plasma drug clearance and platelet loss were similar to those reported for other coated charcoal columns. Cellulose acetate-coated charcoal haemoperfusion may reduce the period of coma in severe poisoning with barbiturates and other hypnotic drugs and thus the morbidity and mortality.