Histologist's original opinion compared with multidisciplinary team in determining diagnosis in interstitial lung disease. Issue 3 (4th November 2016)

• Record Type: Journal Article
• Authors: Burge, PS; Reynolds, J; Trotter, S; Burge, GA; Walters, G
• Other Names: Djearaman Madava author non-byline.; Hussain Shahid author non-byline.; Hoey Ed author non-byline.; Langman Gerald author non-byline.; Payyappilly Sherin author non-byline.; Naidoo Praba author non-byline.; Kalkat Maninder author non-byline.; Steyn Richard author non-byline.; Rajesh Pala author non-byline.; Bishay Ehab author non-byline.; Naidu Babu author non-byline.; Ghani Salman author non-byline.; Petkova Dimitrina author non-byline.; Robertson Alastair author non-byline.; Jayakumar J author non-byline.
• Is Part Of: Thorax. Volume 72:Issue 3(2017)
• Page Start: 280
• Page End: 281
• Publication Date: 2016-11-04
• Subjects: Hypersensitivity pneumonitis -- Histology/Cytology -- Idiopathic pulmonary fibrosis -- Interstitial Fibrosis -- Rheumatoid lung disease -- Sarcoidosis; Chest -- Diseases -- Periodicals; Thorax; Chest -- Diseases; Periodicals; Periodicals; 617.54
• DOI: 10.1136/thoraxjnl-2016-208776
• Languages: English
• ISSNs: 0040-6376

Abstract

Abstract : Guidelines recommend that multidisciplinary interstitial lung disease meeting (ILD MDT) decisions become the gold standard for diagnosis, replacing the histologist from this position, and identify this as requiring supportive evidence. We have compared diagnoses from lung biopsy material made by expert histologists with the subsequent consensus opinion from a properly constituted ILD MDT in 71 consecutive patients referred to a regional thoracic unit. MDT changed the original histological diagnoses in 30% (95% CI 19.3% to 41.6%) and strengthened the diagnoses from probable to confident in a further 17% (95% CI 9.1% to 27.7%). The assessment of hypersensitivity pneumonitis, non-necrotising granulomas and organising pneumonia accounted for the majority of the changes.