IDDF2019-ABS-0272 Clinical profile of patients with acute mesenteric ischemia in northern india. (7th June 2019)

• Record Type: Journal Article
• Authors: Agrawal, Jatin; Arora, Anil; Anikhindi, Shrihari Anil; Singla, Vikas; Sharma, Praveen
• Is Part Of: Gut. Volume 68(2019)Supplement 1
• Page Start: A112
• Page End: A112
• Publication Date: 2019-06-07
• Subjects: Gastroenterology -- Periodicals; 616.33
• DOI: 10.1136/gutjnl-2019-IDDFAbstracts.217
• Languages: English
• ISSNs: 0017-5749

Abstract

Abstract : Background: Acute mesenteric ischemia (AMI) is a medical emergency and constitutes around 0.09–0.2% of all cases of acute abdomen, with 50% in-hospital mortality. According to Western literature, AMI most commonly occurs in the 7 th -8 th decade, with 50% mortality, and arterial occlusion being the most common cause. The clinical profile of patients of AMI in India may be different from Western patients; however, the data is lacking. We aimed to study the clinical profile of patients of AMI at a tertiary care centre in northern India. Methods: We retrospectively collected data of consecutive patients of AMI admitted our department from March 2014 to Jan 2019. Data regarding epidemiology, clinical presentation, etiology, imaging, treatment and outcome were studied. Results: Our study included 59 patients (74% males, median age 52 years). The most common presentation was pain abdomen in 88%, obstipation 40%, gastrointestinal bleeding 17%, and peritonitis 0.5%. Mesenteric Venous thrombosis was seen in 56%, mesenteric artery thrombosis in 30%, mixed thrombosis in 10% and non-occlusive ischemia in 3%. Most (71%) patients required surgical resection. The overall in-hospital mortality was 34%. Conclusions: Unlike the Western literature, the AMI in North India is most commonly due to venous thrombosis, presenting in the sixth decade, and has a lower mortality rate than West. Large prospective studies will be required to elucidate the cause of these differences from Western data.