IDDF2019-ABS-0324 Appropriateness of prescribing proton pump inhibitor in a tertiary care superspeciality hospital in india. (June 2019)

• Record Type: Journal Article
• Authors: Kamat, Nagesh; Shetty, Shiran; Bhatia, Sumit; Shetty, Anurag
• Is Part Of: Gut. Volume 68(2019)Supplement 1
• Page Start: A119
• Page End: A119
• Publication Date: 2019-06
• Subjects: Gastroenterology -- Periodicals; 616.33
• DOI: 10.1136/gutjnl-2019-IDDFAbstracts.232
• Languages: English
• ISSNs: 0017-5749

Abstract

Abstract : Background: Proton Pump Inhibitor (PPI) is the commonest prescribed drug in gastroenterology practice due to its proven effectiveness for a variety of indications. Long-term use contributes to adverse events. There is a large unmet need to evaluate the appropriateness of prescribing PPI therapy. Methods: A cross-sectional study was conducted over three months at a Gastroenterology outpatient department of a tertiary care teaching hospital. Adult patients who were prescribed PPI were interviewed . Patient medication charts were reviewed and demographic details, PPI use, dose, regimen and valid indication for PPI prescription was noted in accordance with international guidelines and best evidence. Results: Three forty-one (male 240; 70.4%) patients were included. Their median age was 35 (range 18–78) years. 191(56%), 84(24.6%) and 56 (16.4%) of the patients received oral Rabeprazole, Pantoprazole and Esomeprazole respectively. Rest were prescribed a combination of PPI with prokinetic (Domperidone/Itopride). The commonest indication was Gastroesophageal Reflux Disease followed by Pancreatitis. Overall, 10(2.9%) of the patients were receiving PPIs without an appropriate indication out of which 3 were on self-medication. 85(24.9%) patients had a previous PPI prescription, and 256(75.1%) were initiated on PPI therapy during their current visit. The median duration of therapy was 4.5 weeks. Conclusions: Majority of the patients (97.1%) had an identifiable and appropriate PPI indication. Accurate PPI prescribing can reduce the incidence of adverse events and contribute to overall cost savings. Nevertheless, patients should be educated and warned regarding self-medication and inappropriate use. Meanwhile, doctors need to reevaluate drugs at follow up, reduce dose and stop accordingly.