Polymyxin B-modified conjugated oligomer nanoparticle for targeted identification and enhanced photodynamic antimicrobial therapy. Issue 85 (11th October 2021)

• Record Type: Journal Article
• Authors: Jiang, Qi; Yan, Xinrong; Jiao, Dan; Zhang, Jiangyan; Wu, Yonggang; Cheng, Yongqiang
• Is Part Of: Chemical communications. Volume 57:Issue 85(2021)
• Page Start: 11244
• Page End: 11247
• Publication Date: 2021-10-11
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/d1cc04389g
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : A photosensitive polymyxin B-modified conjugated oligomer nanoparticle that integrates the targeted identification and synergistic photodynamic therapy in one treatment against resistant Gram-negative bacteria. Abstract : We report a photosensitive polymyxin B-modified conjugated oligomer nanoparticle that integrates the targeted identification and synergistic photodynamic therapy in one treatment against resistant Gram-negative bacteria. The study expands the application of antibiotics and opens a new avenue for enhancing photodynamic antimicrobial therapy and fighting bacterial resistance.