Controlled covalent functionalization of a graphene-channel of a field effect transistor as an ideal platform for (bio)sensing applications. Issue 10 (25th August 2021)

• Record Type: Journal Article
• Authors: Mishyn, Vladyslav; Rodrigues, Teresa; Leroux, Yann R.; Aspermair, Patrik; Happy, Henri; Bintinger, Johannes; Kleber, Christoph; Boukherroub, Rabah; Knoll, Wolfgang; Szunerits, Sabine
• Is Part Of: Nanoscale horizons. Volume 6:Issue 10(2021)
• Page Start: 819
• Page End: 829
• Publication Date: 2021-08-25
• Subjects: Nanoscience -- Periodicals; Nanotechnology -- Periodicals; 620.505
• DOI: 10.1039/d1nh00355k
• Languages: English
• ISSNs: 2055-6756

Abstract

Abstract : Electrochemical grafting of a protected ethynylphenyl diazonium salt leads to the deposition of a functional monolayer on the graphene channel of a field effect transistor, leading to a general platform for (bio)sensing applications. Abstract : The controlled covalent functionalization of the graphene channel of a field effect transistor, based on interdigitated gold electrodes (source and drain), via electrochemical grafting, using specifically designed aryl diazonium species is demonstrated to allow the simple fabrication of a general platform for (bio)sensing applications. The electrochemical grafting of a protected ethynylphenyl diazonium salt leads to the deposition of only a monolayer on the graphene channel. This controlled covalent functionalization of the graphene channel results in a charge mobility of the GFET of 1739 ± 376 cm 2 V −1 s −1 and 1698 ± 536 cm 2 V −1 s −1 for the holes and electrons, respectively, allowing their utilization as (bio)sensors. After deprotection, a dense and compact ethynylphenyl monolayer is obtained and allows the immobilization of a wide range of (bio)molecules by a "click" chemistry coupling reaction (Huisgen 1, 3-dipolar cycloaddition). This finding opens promising options for graphene-based (bio)sensing applications.