Synthesis of 2-iminothiazolidin-4-ones using guanine functionalized SBA-16 as a solid base catalyst. (23rd November 2021)

• Record Type: Journal Article
• Authors: Gupta, Radha; Pathak, Devendra Deo
• Is Part Of: Tetrahedron letters. Volume 85(2021)
• Publication Date: 2021-11-23
• Subjects: 2-Iminothiazolidin-4-ones -- Heterogeneous catalyst -- Solid base -- Guanine-functionalized SBA-16; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2021.153497
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: Graphical representation of 2-iminothiazolidin-4-ones synthesis using metal-free heterogeneous catalyst SBA-16@G. Abstract: The first example of a one-pot three-component tandem annulation approach is described for the synthesis of 2-iminothiazolidin-4-ones by the reaction of aromatic/aliphatic amines, aryl isothiocyanates, and ethyl bromoacetate, catalysed by guanine-functionalized SBA-16, [SBA-16@G], as an efficient and recyclable heterogeneous solid base catalyst. The methodology is simple and offers a broad-substrate scope under mild reaction conditions.