Computer simulation of the dynamics of a spatial susceptible-infected-recovered epidemic model with time delays in transmission and treatment. (November 2021)

• Record Type: Journal Article
• Authors: Tiomela, Sedrique A.; Macías-Díaz, J.E.; Mvogo, Alain
• Is Part Of: Computer methods and programs in biomedicine. Volume 212(2021)
• Publication Date: 2021-11
• Subjects: SIR model -- Spatial diffusion -- Transmission and treatment delay -- Basic reproduction number -- Nonlinear bifurcation analysis -- Complex pattern formation; 65Mxx -- 65Qxx; Medicine -- Computer programs -- Periodicals; Biology -- Computer programs -- Periodicals; Computers -- Periodicals; Medicine -- Periodicals; Médecine -- Logiciels -- Périodiques; Biologie -- Logiciels -- Périodiques; Biology -- Computer programs; Medicine -- Computer programs; Periodicals; Electronic journals; 610.28
• DOI: 10.1016/j.cmpb.2021.106469
• Languages: English
• ISSNs: 0169-2607

Abstract

Highlights: A SIR epidemic model with multiple time delays is studied analytically and numerically. Conditions on the backward bifurcation are established. Critical transmission and treatment delays are determined analytically. The computer implementations capture some key features on the pattern formation in epidemic systems. Abstract: Background and objective: In this work, we analyze the spatial-temporal dynamics of a susceptible-infected-recovered (SIR) epidemic model with time delays. To better describe the dynamical behavior of the model, we take into account the cumulative effects of diffusion in the population dynamics, and the time delays in both the Holling type II treatment and the disease transmission process, respectively. Methods: We perform linear stability analyses on the disease-free and endemic equilibria. We provide the expression of the basic reproduction number and set conditions on the backward bifurcation using Castillo's theorem. The values of the critical time transmission, the treatment delays and the relationship between them are established. Results: We show that the treatment rate decreases the basic reproduction number while the transmission rate significantly affects the bifurcation process in the system. The transmission and treatment time-delays are found to be inversely proportional to the susceptible and infected diffusion rates. The analytical results are numerically tested. The results show that the treatment rate significantly reduces the density of infected population and ensures the transition from the unstable to the stable domain. Moreover, the system is more sensible to the treatment in the stable domain. Conclusions: The density of infected population increases with respect to the infected and susceptible diffusion rates. Both effects of treatment and transmission delays significantly affect the behavior of the system. The transmission time-delay at the critical point ensures the transition from the stable (low density) to the unstable (high density) domain.