151 Screening for cervical cancer in a tunisian hospital. (18th September 2019)

• Record Type: Journal Article
• Authors: Ben Amor, A; Bacha, D; Saffar, K; Halouani, A; Lahmar, A; Ben Slama, S; Bouraoui, S; Amel, T
• Is Part Of: International journal of gynecological cancer. Volume 29(2019)Supplement 3
• Page Start: A69
• Page End: A70
• Publication Date: 2019-09-18
• Subjects: Generative organs, Female -- Cancer -- Periodicals; 616.99465
• DOI: 10.1136/ijgc-2019-IGCS.151
• Languages: English
• ISSNs: 1048-891X

Abstract

Abstract : Objectives: To analyze the epidemiological, clinical and cyto-colo-histological data of patients who carried out colposcopy. Methods: Prospective study, conducted during 4 years in the Gynecology department of our institution. We included all patients who had colposcopy, regardless of indication and without gynecological neoplastic pathology. Results: Our study included 110 patients with so many pap smears: atypical squamous cells of undetermined significance (48%), high grade squamous intraepithelial lesions (HSIL) (11%), atypical squamous cells cannot exclude HSIL (22%), low grade squamous intraepithelial lesions (14%), atypical glandular cells (5%). Colposcopy showed atypical transformation: grade 1 (ATG 1) in 34% and grade 2 (ATG 2) in 66% of cases. Cervical biopsy revealed normal cervical squamous mucosa in 8%, cervicitis in 72% and condyloma in 8%. A case of CIN 1 was found in 6%, CIN 2 in 3% and CIN 3 in 2%. Cervical biopsy revealed one squamous cell carcinoma. Coloscopy sensitivity was 77% and specificity of 37%. The positive predictive value was 24% and the negative predictive value was 86%. For high grade dysplasia, colposcopy had a sensitivity of 100%, a specificity of 37%. A conization was performed in nine patients for squamous cell carcinoma or high grade dysplasia. Conization was performed in a patient with cyto-histological discordance. Histological study rebealed an in situ carcinoma in two cases. Conclusions: Our results showed that ATG 1 lesions at colposcopy regardless of the FCU abnormalities are predictive of benign biopsy lesions. We also tend to overestimate the ATG 2 lesions.