149 Impact of pelvic lymph nodes metastasis on recurrence in patients with early cervical cancer. (18th September 2019)

• Record Type: Journal Article
• Authors: Montero Macías, R; Balaya, V; Bonsans-Kitsis, H; Bats, AS; Delomenie, M; Ngo, C; Koual, M; Nguyen-Xuan, HT; Gomes David, M; De Jesus, J; Bresset, A; Osdoit, M; Khidder, H; Lecuru, F
• Is Part Of: International journal of gynecological cancer. Volume 29(2019)Supplement 3
• Page Start: A68
• Page End: A69
• Publication Date: 2019-09-18
• Subjects: Generative organs, Female -- Cancer -- Periodicals; 616.99465
• DOI: 10.1136/ijgc-2019-IGCS.149
• Languages: English
• ISSNs: 1048-891X

Abstract

Abstract : Objectives: We studied the different risk factors to involvement lymph pelvic node and to recurrence in patients with early cervical cancer in our population. Methods: We retrospectively analysed the data from 85 patients with early cervical cancer treated at the European Hospital George Pompidou in Paris between January 2004 and June 2018. Inclusion criteria: patients with cervical cancer stage IA1- IIA. Exclusion criteria: missing or insufficient follow-up data (< 6 months), not node stage evaluation and patients who received neoadjuvant radiochemotherapy. The chi-square test (or Fisher's test if sample size too small) was used to compare qualitative variables. A value of p=0.05 was used as the limit of statistical significance in the parametric analyses NS = no significance. Results: Conclusions: Many factors for recurrence have been described in patients with cervical cancer. Lymph node involvement is considered the main prognostic factor. Other prognostic factors for recurrence are tumour size, maximum stromal invasion, and presence or absence of lymphovascular space involvement (LVSI) have been evaluated. Different factors had been associated for risk to involvement lymph pelvic nodes: depth of invasion parametrial involvement, lymphatic-vascular space invasion, tumor grade and size of primary tumor. We don´t find any factors associated with the risk of involved nodes. The only factor associated with the risk of recurrence was tumor size.