Evaluation of a fully automated and completely quantitative allergen-specific IgE and total IgE detection assay. Issue 35 (16th August 2021)

• Record Type: Journal Article
• Authors: Huang, Huimin; Huang, Zhifeng; Zheng, Peiyan; Wei, Nili; Liang, Xueqing; Li, Wanjia; Sun, Baoqing
• Is Part Of: Analytical methods. Volume 13:Issue 35(2021)
• Page Start: 3940
• Page End: 3946
• Publication Date: 2021-08-16
• Subjects: Chemistry, Analytic -- Periodicals; Analytical biochemistry -- Periodicals; Chemical laboratories -- Standards -- Periodicals; 543.1905
• DOI: 10.1039/d1ay01172c
• Languages: English
• ISSNs: 1759-9660

Abstract

Abstract : Based on the current urgent need for an in vitro quantitative detection system for allergens in China, we introduced a novel allergen sIgE detection system that employs a solid phase enzyme-linked immunoassay and evaluated its clinical performance. Abstract : Based on the current urgent need for an in vitro quantitative detection system for allergens in most hospitals in China, we introduced a novel allergen-specific immunoglobulin E detection system that employs a solid phase enzyme-linked immunoassay and evaluated its clinical performance. The system uses a special reaction component (innovative patents) to reduce the reaction time to 12 min, achieving point-of-care testing for allergy management, which is impressive compared to the 3–18 h testing time for all other systems. In addition, the AILEX system has excellent consistency with the ImmunoCAP reference method system; therefore, we recommend the introduction of the AILEX system for clinical auxiliary diagnosis in medical units.