Metal-free sulfonylative annulations of alkyl diiodides with sulfur dioxide: synthesis of cyclic aliphatic sulfones. Issue 19 (3rd August 2021)

• Record Type: Journal Article
• Authors: Jia, Xiuwen; Huang, Chunxi; Zhang, Xuemei; Lian, Zhong
• Is Part Of: Organic chemistry frontiers. Volume 8:Issue 19(2021)
• Page Start: 5310
• Page End: 5315
• Publication Date: 2021-08-03
• Subjects: Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1039/d1qo00804h
• Languages: English
• ISSNs: 2052-4110

Abstract

Abstract : A straightforward protocol for cyclic aliphatic sulfones is effectively established via sulfonylative annulations of alkyl diiodides and gaseous sulfur dioxide. Five- to nine-membered cyclic aliphatic sulfones were afforded in this manner. Abstract : A straightforward protocol for cyclic aliphatic sulfones is effectively established via sulfonylative annulations of alkyl diiodides and gaseous sulfur dioxide. In this transformation, SOgen serves as a safe, bench-stable and convenient SO2 -surrogate. Five- to nine-membered cyclic aliphatic sulfones were smoothly afforded in an efficient manner. This protocol features moderate to high yields, good functional group compatibility and mild reaction conditions.