Neurocutaneous melanocytosis‐associated malignant melanoma presenting with peritoneal seeding. Issue 5 (31st August 2021)

• Record Type: Journal Article
• Authors: Sener, Ugur; Elmore, Kevin; Jayaseelan, Keerthana; Porter, Joanne; Marghoob, Ashfaq; Rosenblum, Marc K.; Haque, Sofia; Khakoo, Yasmin
• Is Part Of: Pediatric dermatology. Volume 38:Issue 5(2021)
• Page Start: 1298
• Page End: 1301
• Publication Date: 2021-08-31
• Subjects: meningeal carcinomatosis -- neoplasms malignant -- neurocutaneous disorders -- nevi‐melanocytic -- peritoneal carcinomatosis; Pediatric dermatology -- Periodicals; Children -- Diseases -- Periodicals; 618.925
• DOI: 10.1111/pde.14789
• Languages: English
• ISSNs: 0736-8046

Abstract

Abstract: Neurocutaneous melanocytosis (NCM) is characterized by melanocyte deposition in the leptomeninges and brain parenchyma, primarily occurring in children with large or giant congenital melanocytic nevi (LCMN) or multiple congenital melanocytic nevi. Patients with NCM may develop hydrocephalus and increased intracranial pressure, which can be managed with ventriculoperitoneal (VP) shunting. We present the case of a 16‐month‐old girl who developed peritoneal carcinomatosis and malignant ascites following VP shunting for hydrocephalus secondary to NCM to increase awareness of this rare, but serious, complication of cerebrospinal fluid diversion.