The organocatalytic synthesis of perfluorophenylsulfides via the thiolation of trimethyl(perfluorophenyl)silanes and thiosulfonates. Issue 42 (14th October 2021)

• Record Type: Journal Article
• Authors: Luo, Jinyun; Lin, Muze; Wu, Leifang; Cai, Zhihua; He, Lin; Du, Guangfen
• Is Part Of: Organic & biomolecular chemistry. Volume 19:Issue 42(2021)
• Page Start: 9237
• Page End: 9241
• Publication Date: 2021-10-14
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/d1ob01350e
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : The organic superbase t -Bu-P4 -catalyzed direct thiolation of trimethyl(perfluorophenyl)silanes and thiosulfonates was developed. Abstract : The organic superbase t -Bu-P4 -catalyzed direct thiolation of trimethyl(perfluorophenyl)silanes and thiosulfonates was developed. Yields of perfluorophenylsulfides of up to 97% under catalysis of 5 mol% t -Bu-P4 were achieved. This method was shown to provide an efficient way to construct the perfluorophenyl–sulfur bond under mild metal-free reaction conditions.