Visible-light-promoted divergent functionalizations of methylenecyclopropanes. Issue 22 (23rd September 2021)

• Record Type: Journal Article
• Authors: Zhu, Baoxiang; Wang, Zhao; Xi, Hui; Feng, Zengqiang; Wang, Binglei; Jiao, Wenyang; Li, Zhongxian; Wang, Zechao; Wu, Junliang
• Is Part Of: Organic chemistry frontiers. Volume 8:Issue 22(2021)
• Page Start: 6300
• Page End: 6308
• Publication Date: 2021-09-23
• Subjects: Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1039/d1qo01187a
• Languages: English
• ISSNs: 2052-4110

Abstract

Abstract : Visible-light-induced monofunctionalization and difunctionalization of MCPs via ring-opening and cyclization processes have been developed for the syntheses of difluoromethyl compounds, alkyl compounds, halides, and sulfonyl compounds. Abstract : Simple and convenient visible-light-promoted radical monofunctionalization and difunctionalization of methylenecyclopropanes via ring-opening and cyclization processes have been developed for the syntheses of difluoromethyl compounds, alkyl compounds, halides, and sulfonyl compounds in moderate to excellent yields. The methodologies feature a wide substrate scope and tolerate various functional groups. A possible radical mechanism has been investigated and proven as a single electron transfer (SET) procedure.