Topical chemotherapy for ocular surface squamous neoplasia: current status. Issue 5 (23rd September 2009)

• Record Type: Journal Article
• Authors: Sepulveda, Ricardo; Pe'er, Jacob; Midena, Edoardo; Seregard, Stefan; Dua, Harminder S; Singh, Arun D
• Is Part Of: British journal of ophthalmology. Volume 94:Issue 5(2010)
• Page Start: 532
• Page End: 535
• Publication Date: 2009-09-23
• Subjects: Ocular surface; Ophthalmology -- Periodicals; 617.7
• DOI: 10.1136/bjo.2009.160820
• Languages: English
• ISSNs: 0007-1161

Abstract

Abstract : Although there are no randomised trials directly comparing topical chemotherapeutic agents mitomycin-C, 5-fluorouracil, and interferon-α2b, published studies indicate equal efficacy of these agents for treatment of non-invasive ocular surface squamous neoplasia (80%–88%). 5-Fluorouracil may be preferred, given low incidence of serious side effects and low cost to the patient.