ASSA13-16-5 The Difference of Postprandial Plasma Triglyceride, Adiponectin and C-Reactive Protein Between Young and Middle Age Men. (29th April 2013)

• Record Type: Journal Article
• Authors: Chenghong, Liao; Juxiang, Li; Zhihong, Zhang; Hai, Su; Qiang, Peng
• Is Part Of: Heart. Volume 99(2013)Supplement 1
• Page Start: A77
• Page End: A77
• Publication Date: 2013-04-29
• Subjects: Heart -- Diseases -- Treatment -- Periodicals; Cardiology -- Periodicals; 616.12
• DOI: 10.1136/heartjnl-2013-303992.239
• Languages: English
• ISSNs: 1355-6037

Abstract

Abstract : Objective: The profile of postprandial plasma adiponectin and high-sensitivity C-reactive protein (hsCRP) is unclear in young persons and middle-aged men. Methods: This study included 11 young men (18.9 ± 1.7 year) and 11 (40.8 ± 3.8year) body mass indexes (BMI) matched middle –aged men (22.8 ± 4.58 vs 22.7 ± 4.40, NS). The plasma triglyceride (TG) levels were measured before and at 2, 4 and 6 hours after a fat meal, and adiponectin and hsCRP were measured before and 2 hour after fat meal. Results: The fasting TG level was higher in middle-age group than in young group. The postprandial TG levels at 2, 4 and 6h decreased in the young group, but increased in middle age men. The TG-AUC was significantly higher in middle age men than in young men (2.41 ± 1.31 vs –0.84 ± 1.19, h.mmol/L, P < 0.05). The fasting adiponectin and hsCRP levels were similar between two groups. Both groups showed significantly increased postprandial adiponectin and hsCRP levels with similar increase amplitudes, so the postprandial adiponectin and hsCRP levels were also similar. Conclusions: The postprandial TG levels after a fat meal are associated with age. Although middle-aged men have significant higher postprandial TG levels, the 2 h postprandial adiponectin and hsCRP levels are similar to those of the young men.