Combination of ankle-brachial index and coronary artery calcium score as a predictor for 3-vessel coronary artery disease in older patients. (12th October 2011)

• Record Type: Journal Article
• Authors: Yang, Chengming; Lan, Yunjing; Zeng, Chunyu; Fang, Yuqiang; Chen, Peng
• Is Part Of: Heart. Volume 97(2011)Supplement 3
• Page Start: A136
• Page End: A136
• Publication Date: 2011-10-12
• Subjects: Heart -- Diseases -- Treatment -- Periodicals; Cardiology -- Periodicals; 616.12
• DOI: 10.1136/heartjnl-2011-300867.397
• Languages: English
• ISSNs: 1355-6037

Abstract

Abstract : Objective: To get the sensitivity, specificity and accuracy of ankle-brachial index (ABI) and coronary artery calcium score (CACS) to judge the 3-vessel coronary artery lesions. Furthermore, to investigate whether the value of judge the 3-vessel coronary artery lesions can be improved when combining both of the two methods. All those is to find a non-invasive and inexpensive method with good sensitivity and specificity. Methods: According to the results of CAG, 96 older patients who had underwent ABI and CACS measurement were divided into two groups: group of 3-vessel artery lesions and the control group. The baseline information were compared to investgate whether there were differences in the two groups. The best cut-points of ABI and CACS were analysis by ROC, and the parallel test were analysed to investgate whether combining the two can improve their diagnosis value. Results: The baseline information between the two groups is no significant difference. As compared, ABI<0.9 and CACS>400 were the best cut-point value with maxinm youdens index which was determined by ROC. ABI<0.9 and CACS>400 were independence predictors of the 3-vessel lesions. The sensitvity and specificity of ABI<0.9 to predict 3-vessel lesions were 58% and 87%, the sensitvity and specificity of CACS>400 of that were 64% and 86%, and that of parallel test were 85% and 83%. Whose sensitivity significantly increased (p<0.05) and specificity has dropped, but the difference was not statistically significant. Conclusions: ABI<0.9 and CACS>400 were the best cut-point value and independence predictors for the 3-vessel lesions. The cut-off point of ABI<0.9 and CACS>400 for the determination of 3-vessel coronary lesions had high respectivity but relatively low sensitivity. The parallel test of combine ABI<0.9 and CACS>400 greatly increased the sensitivity and specificity was not significantly decreased. Combining use is more practical value.