Evolving Cardiac Electrical Therapies for Advanced Heart Failure Patients. (16th April 2021)

• Record Type: Journal Article
• Authors: Sharif, Zain I.; Galand, Vincent; Hucker, William J.; Singh, Jagmeet P.
• Is Part Of: Circulation. Volume 14:Number 4(2021)
• Page Start: e009668
• Publication Date: 2021-04-16
• Subjects: disease management -- heart failure -- humans -- myocardial contraction -- pressoreceptors; Arrhythmia -- Periodicals; Heart -- Electric properties -- Periodicals; 616.128
• DOI: 10.1161/CIRCEP.120.009668
• Languages: English
• ISSNs: 1941-3149

Abstract

Abstract : Symptomatic heart failure (HF) patients despite optimal medical therapy and advances such as invasive hemodynamic monitoring remain challenging to manage. While cardiac resynchronization therapy remains a highly effective therapy for a subset of HF patients with wide QRS, a majority of symptomatic HF patients are poor candidates for such. Recently, cardiac contractility modulation, neuromodulation based on carotid baroreceptor stimulation, and phrenic nerve stimulation have been approved by the US Food and Drug Administration and are emerging as therapeutic options for symptomatic HF patients. This state-of-the-art review examines the role of these evolving electrical therapies in advanced HF.