Effect of the hydrophilicity of acrylic intraocular lens material and haptic angulation on anterior capsule opacification. Issue 4 (15th November 2006)

• Record Type: Journal Article
• Authors: Vock, Lorenz; Georgopoulos, Michael; Neumayer, Thomas; Buehl, Wolf; Findl, Oliver
• Is Part Of: British journal of ophthalmology. Volume 91:Issue 4(2007)
• Page Start: 476
• Page End: 480
• Publication Date: 2006-11-15
• Subjects: ACO, anterior capsule opacification -- ALG, anterolenticular gap -- CCC, continuous curvilinear capsulorhexis -- IOL, intraocular lens -- LEC, lens epithelial cell; acrylic intraocular lens -- anterior capsule opacification -- ACO -- haptic angulation; Ophthalmology -- Periodicals; 617.7
• DOI: 10.1136/bjo.2006.103390
• Languages: English
• ISSNs: 0007-1161

Abstract

Abstract : Aim: To evaluate the influence of hydrophilic and hydrophobic acrylic material and haptic angulation on anterior capsule opacification (ACO). Methods: Prospective study on 53 patients with bilateral age-related cataract. Patients underwent standard cataract surgery by the same surgeon and randomly received a hydrophilic acrylic intraocular lens (IOL) in one eye and a hydrophobic acrylic IOL in the other eye. Forty five of these patients completed the one-year follow-up. The following parameters were assessed: decentration, buttonholing, anterolenticular gap (ALG), ACO, outgrowth and refractive outcome. Results: At the one-year follow-up, ACO was seen in 80% of the hydrophilic and 100% of the hydrophobic IOLs. ACO was more intense in the hydrophobic IOLs (p<0.001). Outgrowth was seen in 42% of the hydrophilic and 2% of the hydrophobic IOLs (p = 0.0003). No case of persisting ALG was seen in the hydrophobic IOLs, but in 42% of the hydrophilic IOLs. The refractive outcome was −0.29 (SD 0.56) dioptres for the hydrophilic and 0.003 (SD 0.44) dioptres for the hydrophobic IOLs (p<0.001). Conclusion: These results suggest that there is less ACO in hydrophilic acrylic than in hydrophobic acrylic IOLs. Although material properties might play a role, the angulated haptics of the hydrophilic IOLs exert an additional effect by the persisting ALG and a lack of contact between the IOL and the anterior capsule.