Constituents of Aegle marmelos from Myanmar. Issue 9 (2nd September 2021)

• Record Type: Journal Article
• Authors: Aung, Hnin Thanda; Zar, Thu; Sein, Myint Myint; Komori, Yumiko; Vidari, Giovanni; Takaya, Yoshiaki
• Is Part Of: Journal of Asian natural products research. Volume 23:Issue 9(2021)
• Page Start: 844
• Page End: 850
• Publication Date: 2021-09-02
• Subjects: Aegle marmelos -- Rutaceae -- coumarins -- cytotoxicity -- radical scavenging activity; Materia medica -- Asia -- Periodicals; Pharmacognosy -- Asia -- Periodicals; Medicinal plants -- Asia -- Periodicals; Medicine, Oriental -- Asia -- Periodicals; 615.321095
• DOI: 10.1080/10286020.2020.1804378
• Languages: English
• ISSNs: 1028-6020

Abstract

Abstract: Five compounds (1 –5 ), including three coumarins (1 –3 ) and two alkaloids (4, 5 ) were isolated during the first investigation of the stem bark of Aegle marmelos (L.) Corrêa. collected in Myanmar. Their structures were determined by NMR spectra analysis. Among them, 7´- O -ethylmarmin (1 ) and 2- O -ethyltembamide (5 ) were identified as new compounds. Skimmianine (4 ) showed moderate cytotoxicity against a HeLa cell line, and 7´- O -ethylmarmin (1 ), marmin (2 ), and (+)-epoxyaurapten (3 ) displayed weak radical scavenging activity according to a DPPH scavenging assay. Graphical abstract: UF0001