Vinyl sulfone synthesis via copper-catalyzed three-component decarboxylative addition. Issue 36 (1st September 2021)

• Record Type: Journal Article
• Authors: An, Seunghwan; Song, Kwang Ho; Lee, Sunwoo
• Is Part Of: Organic & biomolecular chemistry. Volume 19:Issue 36(2021)
• Page Start: 7827
• Page End: 7831
• Publication Date: 2021-09-01
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/d1ob01435h
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : The synthesis of vinyl sulfone derivatives via the reaction of arylpropiolic acids, K2 S2 O5, and aryl boronic acids is reported. Abstract : The synthesis of vinyl sulfone derivatives via the reaction of arylpropiolic acids, K2 S2 O5, and aryl boronic acids is reported. The CuBr2 /1, 10-phenanthroline catalytic system in the presence of acetic acid provides the desired vinyl sulfones in moderate to good yield. Furthermore, the methodology features excellent functional group tolerance.