Central serous chorioretinopathy: risk factors for serous retinal detachment in fellow eyes. Issue 6 (31st August 2019)

• Record Type: Journal Article
• Authors: Shinojima, Ari; Mehanna, Chadi; Lavia, Carlo Alessandro; Gaudric, Alain; Tadayoni, Ramin; Bousquet, Elodie
• Is Part Of: British journal of ophthalmology. Volume 104:Issue 6(2020)
• Page Start: 852
• Page End: 856
• Publication Date: 2019-08-31
• Subjects: Retina -- Macula -- Diagnostic tests/Investigation -- Imaging; Ophthalmology -- Periodicals; 617.7
• DOI: 10.1136/bjophthalmol-2019-314970
• Languages: English
• ISSNs: 0007-1161

Abstract

Abstract : Background/Aims: To assess risk factors for serous retinal detachment (SRD) in the fellow eye of patients with central serous chorioretinopathy (CSC) based on clinical data and multimodal imaging findings, including baseline late-phase indocyanine green angiography (ICGA). Methods: Consecutive patients with unilateral CSC were retrospectively assessed. Inclusion criteria were the availability of late-phase ICGA and a spectral-domain optical coherence tomography (OCT) macular cube for both eyes at baseline and over 3 months. Subsequent OCT of fellow eyes was reviewed to detect the development of SRD during the follow-up. Baseline medical data and multimodal imaging findings were analysed using Kaplan-Meier survival curves (log-rank test). Results: Sixty-eight patients with unilateral CSC were included. An SRD was detected in 19% of fellow eyes during a mean follow-up of 25.8±18.7 months. Hyperfluorescent plaques on midphase ICGA, hypofluorescent foci on late-phase ICGA, retinal pigment epithelium changes on fundus autofluorescence and fluorescein angiography abnormalities were associated with the occurrence of SRD (log-rank test; p<0.001, p=0.02, p=0.002 and p=0.001, respectively). Conclusion: These results suggest that the fellow eyes with specific findings on multimodal imaging in patients with unilateral CSC should be carefully followed up for possible incidence of CSC.