A portable thermal detection method based on the target responsive hydrogel mediated self-heating of a warming pad. Issue 77 (7th September 2021)

• Record Type: Journal Article
• Authors: Tang, Juan; Liu, Liping; Gao, Shan; Qin, Jiao; Liu, Xiaoxuan; Tang, Dianping
• Is Part Of: Chemical communications. Volume 57:Issue 77(2021)
• Page Start: 9862
• Page End: 9865
• Publication Date: 2021-09-07
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/d1cc03733a
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : A simple thermal aptasensor was devised for the sensitive detection of organophosphate pesticides based on the efficient self-heating reaction of a warming pad with a switchable target responsive enzyme-encapsulated three-dimensional DNA hydrogel. Abstract : A simple thermal aptasensing platform was devised for the sensitive detection of organophosphate pesticides (using malathion as a model target) based on the efficient self-heating reaction of a warming pad with a switchable target responsive enzyme-encapsulated three-dimensional (3D) DNA hydrogel using a portable thermometer as a signal readout in this work. The existence of the target malathion would open the catalase-3D network and lots of catalase was released from the hydrogel, which could efficiently convert H2 O2 to an O2 molecule. The product O2 is the critical condition for the self-heating of the warming pad. Thereafter, the temperature was enhanced with the increasing amount of O2 . The strategy displays outstanding specificity, reproducibility and stability. Moreover, this method can be easily extended to monitor other molecules using different aptamer sequences in practical applications.