Singapore Chinese Eye Study: key findings from baseline examination and the rationale, methodology of the 6-year follow-up series. Issue 5 (10th August 2019)
- Record Type:
- Journal Article
- Title:
- Singapore Chinese Eye Study: key findings from baseline examination and the rationale, methodology of the 6-year follow-up series. Issue 5 (10th August 2019)
- Main Title:
- Singapore Chinese Eye Study: key findings from baseline examination and the rationale, methodology of the 6-year follow-up series
- Authors:
- Majithia, Shivani
Tham, Yih Chung
Chee, Miao Li
Teo, Cong Ling
Chee, Miao-Ling
Dai, Wei
Kumari, Neelam
Lamoureux, Ecosse Luc
Sabanayagam, Charumathi
Wong, Tien Yin
Cheng, Ching-Yu - Abstract:
- Abstract : Background/aims: In order to address the eye care needs of the increasing numbers of elderly Chinese globally, there is a need for comprehensive understanding on the longitudinal trends of age-related eye diseases among Chinese. We herein report the key findings from the baseline Singapore Chinese Eye Study (SCES-1), and describe the rationale and methodology of the 6-year follow-up study (SCES-2). Methods: 3353 Chinese adults who participated in the baseline SCES-1 (2009–2011) were invited for the 6-year follow-up SCES-2 (2015–2017). Examination procedures for SCES-2 included standardised ocular, systemic examinations and questionnaires identical to SCES-1. SCES-2 further included new examinations such as optical coherence tomography angiography, and questionnaires to evaluate health impact and economic burden of eye diseases. Results: In SCES-1, the age-adjusted prevalence of best-corrected low vision (VA<6/12, better-seeing eye) and blindness (VA<6/60, better-seeing eye) were 3.4% and 0.2%, respectively. The prevalence rates for glaucoma, age related macular degeneration, and diabetic retinopathy (among diabetics) were 3.2%, 6.8%, 26.2%, respectively. Of the 3033 eligible individuals from SCES-1, 2661 participated in SCES-2 (response rate=87.7%). Comparing with those who did not attend SCES-2, those attended were younger, had higher SES (all p<0.001), but less likely to be a current smoker, to have diabetes, hypertension, hyperlipidaemia (all p≤0.025).Abstract : Background/aims: In order to address the eye care needs of the increasing numbers of elderly Chinese globally, there is a need for comprehensive understanding on the longitudinal trends of age-related eye diseases among Chinese. We herein report the key findings from the baseline Singapore Chinese Eye Study (SCES-1), and describe the rationale and methodology of the 6-year follow-up study (SCES-2). Methods: 3353 Chinese adults who participated in the baseline SCES-1 (2009–2011) were invited for the 6-year follow-up SCES-2 (2015–2017). Examination procedures for SCES-2 included standardised ocular, systemic examinations and questionnaires identical to SCES-1. SCES-2 further included new examinations such as optical coherence tomography angiography, and questionnaires to evaluate health impact and economic burden of eye diseases. Results: In SCES-1, the age-adjusted prevalence of best-corrected low vision (VA<6/12, better-seeing eye) and blindness (VA<6/60, better-seeing eye) were 3.4% and 0.2%, respectively. The prevalence rates for glaucoma, age related macular degeneration, and diabetic retinopathy (among diabetics) were 3.2%, 6.8%, 26.2%, respectively. Of the 3033 eligible individuals from SCES-1, 2661 participated in SCES-2 (response rate=87.7%). Comparing with those who did not attend SCES-2, those attended were younger, had higher SES (all p<0.001), but less likely to be a current smoker, to have diabetes, hypertension, hyperlipidaemia (all p≤0.025). Conclusions: Building on SCES-1, SCES-2 will be one of the few longitudinal population-based eye studies to report incidence, progression, and risk factors of major age-related eye diseases. Findings from this cohort may offer new insights, and provide useful reference information for other Chinese populations elsewhere. … (more)
- Is Part Of:
- British journal of ophthalmology. Volume 104:Issue 5(2020)
- Journal:
- British journal of ophthalmology
- Issue:
- Volume 104:Issue 5(2020)
- Issue Display:
- Volume 104, Issue 5 (2020)
- Year:
- 2020
- Volume:
- 104
- Issue:
- 5
- Issue Sort Value:
- 2020-0104-0005-0000
- Page Start:
- 610
- Page End:
- 615
- Publication Date:
- 2019-08-10
- Subjects:
- epidemiology -- eye (globe) -- vision
Ophthalmology -- Periodicals
617.7 - Journal URLs:
- http://bjo.bmj.com/ ↗
http://bjo.bmjjournals.com/ ↗
http://www.bmj.com/archive ↗ - DOI:
- 10.1136/bjophthalmol-2019-314760 ↗
- Languages:
- English
- ISSNs:
- 0007-1161
- Deposit Type:
- Legaldeposit
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- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - BLDSS-3PM
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