Catalytic epoxidation of β-ionone with molecular oxygen using selenium-doped silica materials. (31st August 2021)

• Record Type: Journal Article
• Authors: Li, Peizi; Cao, Kuanhong; Jing, Xiaobi; Liu, Yonghong; Yu, Lei
• Is Part Of: New journal of chemistry. Volume 45:Number 37(2021)
• Page Start: 17241
• Page End: 17246
• Publication Date: 2021-08-31
• Subjects: Chemistry -- Periodicals; Chimie -- Périodiques; 540
• DOI: 10.1039/d1nj03311e
• Languages: English
• ISSNs: 1144-0546

Abstract

Abstract : Se-doped silica could catalyze the β-ionone epoxidation reaction. Interestingly, by doping with fluorine in the catalyst, the reaction selectivity was significantly enhanced. The metal-free process is suitable for pharmaceutical synthesis. Abstract : A novel Se-doped silica material was fabricated, and this easily prepared material could be used as an efficient recyclable catalyst for β-ionone oxidation. Interestingly, by doping with fluorine in the catalyst, the reaction selectivity was significantly enhanced to produce the important pharmaceutical intermediate β-ionone epoxide selectively. Characterization of the materials indicated that by doping with F, the electropositivity of the catalytic Se species was obviously enhanced due to the strong electron-withdrawing features of F, and this was a key factor for controlling the reaction selectivity in the β-ionone epoxidation reaction. The electropositivity of a silica support might also increase and the reinforced electropositivity of Si sites might be beneficial for the adsorption of a β-ionone substrate and for the contact of the electron-enriched endocyclic CC with the catalyst.