Desolvation induced crystal jumping: reversible hydration and dehydration of a spironolactone–saccharin cocrystal with water as the jumping-mate. Issue 39 (24th September 2021)

• Record Type: Journal Article
• Authors: Chen, Yifu; Jing, Bo; Chang, Zewei; Gong, Junbo
• Is Part Of: CrystEngComm. Volume 23:Issue 39(2021)
• Page Start: 6838
• Page End: 6842
• Publication Date: 2021-09-24
• Subjects: Crystals -- Periodicals; Crystal growth -- Periodicals; Crystallography -- Periodicals; Cristaux -- Périodiques; Cristaux -- Croissance -- Périodiques; Cristallographie -- Périodiques; 548
• DOI: 10.1039/d1ce00830g
• Languages: English
• ISSNs: 1466-8033

Abstract

Abstract : We present a spironolactone–saccharin cocrystal hydrate as the first example of a crystal that jumps without changes in either the lattice parameter or the molecular conformation to highlight the unique advantages of the jumping-mate strategy. Abstract : A jumping crystal of the channel-type hydrate of spironolactone–saccharin cocrystals was presented as the first example of a crystal that jumps without changes in both the lattice constant and the molecular conformation, emphasizing the general applicability of our newly proposed design concept that introduces an easy-to-escape component, the jumping-mate, to generate crystal motions.