Cobalt-catalyzed cross-coupling reactions of aryl- and alkylaluminum derivatives with (hetero)aryl and alkyl bromides. Issue 81 (24th September 2021)

• Record Type: Journal Article
• Authors: Dilauro, Giuseppe; Messa, Francesco; Bona, Fabio; Perrone, Serena; Salomone, Antonio
• Is Part Of: Chemical communications. Volume 57:Issue 81(2021)
• Page Start: 10564
• Page End: 10567
• Publication Date: 2021-09-24
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/d1cc04002b
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : The catalytic activity of cobalt with the soft nucleophilicity of organoaluminum compounds disclosed a robust and scalable process for the formation of new Csp 2 -Csp 2 and Csp 3 -Csp 2 bonds with high functional group compatibility and in mild conditions. Abstract : A simple cobalt complex, such as Co(phen )Cl2, turned out to be a highly efficient and cheap precatalyst for a host of cross-coupling reactions involving aromatic and aliphatic organoaluminum reagents with aryl, heteroaryl and alkyl bromides. New C(sp 2 )–C(sp 2 ) and C(sp 2 )–C(sp 3 ) bonds were formed in good to excellent yields and with high chemoselectivity, under mild reaction conditions.