Innovative nanotools for vascular drug delivery: the atherosclerosis case study. Issue 41 (5th October 2021)

• Record Type: Journal Article
• Authors: De Negri Atanasio, Giulia; Ferrari, Pier Francesco; Campardelli, Roberta; Perego, Patrizia; Palombo, Domenico
• Is Part Of: Journal of materials chemistry. Volume 9:Issue 41(2021)
• Page Start: 8558
• Page End: 8568
• Publication Date: 2021-10-05
• Subjects: Materials -- Periodicals; Chemistry, Analytic -- Periodicals; Biomedical materials -- Research -- Periodicals; 543.0284
• DOI: 10.1039/d1tb01071a
• Languages: English
• ISSNs: 2050-750X

Abstract

Abstract : Nanotechnology represents a new research field for atherosclerosis therapy and diagnosis. Abstract : Cardiovascular diseases are the leading cause of mortality in the Western world. Among them, atherosclerosis represents one of the most common diseases in the modern society due to a common sedentary lifestyle, high-fat diet, and smoking. In the near future, a new approach could potentially improve the therapy of vascular pathologies, where to date the non-specific treatments present several limitations, such as poor biodistribution, quick elimination from the body, and undesired side-effects. In this field, nanotechnology has a great potential for the therapy and diagnosis of atherosclerosis with more and more recent and innovative publications. This review is a critical analysis of the results reported in the literature regarding the different and possible new approaches for the therapy and diagnosis of atherosclerosis.