Catalytic activity of a CuGHK peptide-based porous material. Issue 18 (25th August 2021) - Cirujano, Francisco G.
Abstract : The CuGHK peptide-based porous material acts as a heterogeneous organocatalyst in the Henry reaction due to a periodic distribution of pockets decorated with lysine side chain active sites. Abstract : The CuGHK peptide-based porous material with a periodic distribution of pockets decorated with lysine side chain active sites was synthesized using a room temperature one-step method and used as a heterogeneous organocatalyst. The pockets are capable of benzaldehyde molecule uptake and show high activity in the Henry reaction with nitromethane. Mechanistic pathways are investigated using an integrative experimental/computational approach.