Visible-light-driven photocyclization reaction: photocatalyst-free mediated intramolecular N–N coupling for the synthesis of 2H-indazole-3-carboxamides from aryl azides. Issue 19 (27th July 2021)

• Record Type: Journal Article
• Authors: Liu, Jinni; Liu, Na; Yang, Qingqing; Wang, Long
• Is Part Of: Organic chemistry frontiers. Volume 8:Issue 19(2021)
• Page Start: 5296
• Page End: 5302
• Publication Date: 2021-07-27
• Subjects: Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1039/d1qo00777g
• Languages: English
• ISSNs: 2052-4110

Abstract

Abstract : A visible-light-driven photocyclization reaction of aryl azides to access 2 H -indazole-3-carboxamides in moderate to excellent yields has been realized efficiently under photocatalyst-free and external additive-free conditions. Abstract : In this report, a visible-light-driven photocyclization reaction of aryl azides to access 2 H -indazole-3-carboxamides in moderate to excellent yields has been realized efficiently under photocatalyst-free and external additive-free conditions. An N–N bond coupling was achieved for this N-atom incorporation transformation using an aryl azide as the N-atom source. The transformation of the aryl azide by photocyclization was also achieved under sunlight irradiation. Additionally, this protocol, as a green and sustainable process, possesses some advantages such as broad substrate scope, step- and atom-economy, environmental friendliness and mild reaction conditions.