Catalyst-free [3+2] cycloaddition of azodicarbonyls and o-hydroxyaryl azomethine ylides on water. (22nd October 2021)

• Record Type: Journal Article
• Authors: Wu, Zi-Qiao; Zhang, Mei-Rong; Zhou Han-Chen, Xiao-Yu; Yang, Jia-Le; Zhang, Yu-Heng; Li, Wen-Hai
• Is Part Of: Tetrahedron. Volume 99(2021)
• Publication Date: 2021-10-22
• Subjects: Green reaction -- 1, 2, 4-Triazolines -- On water -- Catalyst-free; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tet.2021.132445
• Languages: English
• ISSNs: 0040-4020

Abstract

Abstract: An environment-friendly methodology for the synthesis of 1, 2, 4-triazoline derivatives on water is described. This method provides an environmental and useful strategy for catalyst-free synthesis of 1, 2, 4-triazolines derivatives. The gram scale reaction and one-pot reaction are also performed to ensure the scalability and high efficiency of the reaction. Graphical abstract: Image 1