A Case of Multiple Perineuriomas in the Colon With Underlying Neurofibromatosis Type I. Issue 9 (4th September 2021)

• Record Type: Journal Article
• Authors: Tsuchiya, Tomoaki; Iwaya, Yugo; Iwaya, Mai; Okamura, Takuma; Nagaya, Tadanobu; Umemura, Takeji
• Is Part Of: ACG Case Reports Journal. Volume 8:Issue 9(2021)
• Page Start: e00665
• Publication Date: 2021-09-04
• DOI: 10.14309/crj.0000000000000665
• Languages: English
• ISSNs: 2326-3253

Abstract

ABSTRACT: A 45-year-old woman was referred to us after a positive fecal occult blood test. Colonoscopy revealed a 20-mm polyp in the transverse colon and a 10-mm polyp in the sigmoid colon. Endoscopic mucosal resection was performed as a diagnostic treatment. Both resected polyps were histologically diagnosed as perineuriomas. She was later found to exhibit multiple café-au-lait spots on the skin and subsequently diagnosed as having neurofibromatosis type I (NF-1). Perineuriomas are rare benign peripheral nerve sheath tumors, with no reports of multiple colonic lesions in a patient with NF-1 to date. NF-1 might be associated with the onset of multiple perineuriomas.