Potential of continuous tPA infusion for multiple-organ failure from lipopolysaccharide-induced disseminated intravascular coagulation in rats. Issue 206 (October 2021)

• Record Type: Journal Article
• Authors: Suga, Yukio; Tashiro, Kiyomichi; Staub, Yukiko; Komura, Shiori; Yamada, Shinya; Morishita, Eriko; Asakura, Hidesaku
• Is Part Of: Thrombosis research. Issue 206(2021)
• Page Start: 84
• Page End: 87
• Publication Date: 2021-10
• Subjects: Disseminated intravascular coagulation -- Lipopolysaccharide -- Tissue plasminogen activator -- Multiple-organ failure -- Inflammatory; Thrombosis -- Periodicals; 616.135
• DOI: 10.1016/j.thromres.2021.08.014
• Languages: English
• ISSNs: 0049-3848

Abstract

Highlights: tPA could show the improvement effect on organ failure. Thrombocytopenia in DIC was suppressed by tPA administration. Renal dysfunction was lower in the LPS + tPA group than in the LPS group.