Breakthroughs and bottlenecks in autophagy research. Issue 9 (September 2021)

• Record Type: Journal Article
• Authors: Mizushima, Noboru; White, Eileen; Rubinsztein, David C.
• Is Part Of: Trends in molecular medicine. Volume 27:Issue 9(2021)
• Page Start: 835
• Page End: 838
• Publication Date: 2021-09
• Subjects: ATG genes -- autophagic flux -- macroautophagy -- neurodegenerative disease -- tumor growth; Molecular biology -- Periodicals; Pathology, Molecular -- Periodicals; Physiology, Pathological -- Periodicals; 572.8
• DOI: 10.1016/j.molmed.2021.06.012
• Languages: English
• ISSNs: 1471-4914

Abstract

Abstract : The study of autophagy has grown exponentially over the past two decades, and significant progress has been made in our understanding of its mechanisms and physiological significance. However, its application to human diseases remains limited. Here, we summarize the current status of autophagy research, with a particular focus on human diseases.