Agreement between the GLIM criteria and PG-SGA in a mixed patient population at a nutrition outpatient clinic. Issue 8 (August 2021)

• Record Type: Journal Article
• Authors: Rosnes, Kristin S.; Henriksen, Christine; Høidalen, Anne; Paur, Ingvild
• Is Part Of: Clinical nutrition. Volume 40:Issue 8(2021)
• Page Start: 5030
• Page End: 5037
• Publication Date: 2021-08
• Subjects: Malnutrition -- GLIM criteria -- PG-SGA -- Validation -- Agreement; BIA Bio electrical impedance analysis -- BMI Body mass index -- CRP C-reactive protein -- DXA dual-energy x-ray absorptiometry -- ESPEN The European Society for Clinical Nutrition and Metabolism -- FFMI Fat-free mass index -- GI Gastrointestinal -- GLIM Global Leadership Initiative on Malnutrition -- ICD-10 International Classification of Diseases, 10th revision -- NPV Negative predictive value -- NRS-2002 Nutritional risk screening 2002 -- PAL Physical activity level -- PG-SGA Patient-Generated Subjective Global Assessment -- PPV Positive predictive value -- SD Standard deviation -- TSD Services for sensitive data -- VAS Verbal analogue scale; Critically ill -- Nutrition -- Periodicals; Diet therapy -- Periodicals; Parenteral feeding -- Periodicals; Enteral feeding -- Periodicals; Enteral Nutrition -- Periodicals; Parenteral Nutrition -- Periodicals; Metabolism -- Periodicals; Diétothérapie -- Périodiques; Alimentation parentérale -- Périodiques; Alimentation entérale -- Périodiques; Nutrition -- Périodiques; Diet therapy; Enteral feeding; Nutrition; Parenteral feeding; Electronic journals; Periodicals; Electronic journals; 615.854
• DOI: 10.1016/j.clnu.2021.07.019
• Languages: English
• ISSNs: 0261-5614

Abstract

Summary: Background & aims: The Global Leadership Initiative on Malnutrition (GLIM) criteria is a step-wise process including a screening tool of choice for risk assessment of malnutrition before assessment of diagnosis and grading of malnutrition severity. The agreement between GLIM and the established malnutrition assessment method Patient Generated-Subjective Global Assessment (PG-SGA) is uncertain. Also, several aspects of GLIM remain to be clearly defined. In this study, we compared diagnosis of malnutrition with the GLIM criteria to the PG-SGA, and explored the differences between the methods. Methods: This cross-sectional study was conducted at the Nutrition Outpatient Clinic at Oslo University Hospital, Norway. Patients were included from September–December 2019. Nutritional Risk Screening 2002 (NRS-2002) was used as the screening tool in the GLIM process before diagnosing and grading the severity of malnutrition. Results are presented with and without the initial risk screening. The diagnostic results from the GLIM process were compared to the malnutrition diagnosis using the PG-SGA. Results: In total, 144 patients, median age 58 years, participated in the study. The full GLIM process identified 36% of the patients as malnourished, while the PG-SGA identified 69% of the patients as malnourished. Comparison of GLIM and PG-SGA showed fair agreement, however the agreement was better when the NRS-2002 screening was excluded. Considering the PG-SGA a gold standard, GLIM had a sensitivity of 51% and a specificity of 98%. The introduction of new cut-off values for fat-free mass did not considerably alter the diagnosis of malnutrition within GLIM. Conclusions: The GLIM criteria showed only fair agreement with the PG-SGA, however the agreement was better when the initial NRS-2002 screening was excluded. A joint consensus on how to perform the GLIM process is needed for comparisons of future studies, and before routine use in clinical practice.